Compound in Broccoli a Potential Weapon Against Breast Cancer
According to new research from the US, a compound found in the popular vegetable broccoli is capable of targeting and killing off cancer stem cells. According to the research, which was published recently in the journal Clinical Cancer Research, the compound sulforaphane was capable of killing off cancer stem cells and prevented new cancerous growths from emerging.
Broccoli vs. cancerous tumors
Collating their data with other earlier studies on the subject, the US researchers noted that sulforaphane was able to reduce the resistance of cancerous tumors to conventional treatment. Since the compound reduces tumor resistance, a second theory arose: the compound may be the key to solving the problem with relapses, or recurring cancer.
The researchers further noted that people who consumed more broccoli tend to have less risk of breast cancer. Since the compound is derived naturally from the vegetable, it has very low toxicity and can be utilized by the body easily (high bioavailability).
Bioavailability is an important concept in medical treatments because if a drug has low bioavailability, it becomes less effective and the patient would eventually need to take higher doses of the drug to get the desired results. To date, sulforaphane has already been marketed as a food supplement. However, the amount of sulforaphane in supplements is not being regulated.
Broccoli vs. diabetes
It seems that like a few other organic compounds like resveratrol, sulforaphane is enjoying widespread popularity because it provides so many benefits. In another study published in the medical journal Diabetes, it was found that the same compound may be helpful in reducing the vascular damage associated with long-term diabetes.
As you may know, diabetes causes a lot of problems to diabetics, including damage to blood vessels. This damage to blood vessels may even cause blindness if the diabetes is not treated and monitored correctly.
Sulforaphane, according to the study in Diabetes, was capable of reducing the damage to body’s blood vessels by activating enzyme production. The enzyme produced protects the blood vessels from the ravages of diabetes.
The compound also helped the body by helping produce enzymes that disabled free radicals in the body. In yet another study, the compound offered hope to family lines with histories of cancer.
It appears that the compound was also capable of preventing cells from passing on damaged or corrupted genetic information to the next generation of cells. In another study (this is the fourth!) sulforaphane was also linked to reducing the chances of aggressive prostate cancer in men by more than forty-five percent.
Sources:
mayoclinic.com
nutraingredients.com
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- “Finish those vegetables before you have your dessert!”: The Importance of Broccoli Concerning Diabetes
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- The Connection Between Vitamins and Breast Cancer Rates
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Posted: May 30th, 2010 under Cancer.
Tags: Breast Cancer, cancer stem cells, Diabetes, family history of cancer, Prostate Cancer, sulforaphane