Grape seed extract is the primary source of a group of powerful antioxidants known as oligomeric proanthocyanidins (OPCs), or generically called pycnogenol, a class of flavonoids. While both pine bark extract and grape seed extract are the primary sources of OPCs, the grape seed extract is more widely recommended because it costs less and it contains an antioxidant not found in pine bark.

Mixtures of complex compounds make up grape seed. It is beneficial in countless ways including preventing cancer and cardiovascular disease & alleviating symptoms of allergies, ulcers, and cataracts. The antioxidant properties found within grape seed extract are believed to help slow the aging process.

Grape seed extract also contains a group of compounds found called procyanidins. By helping them regenerate after neutralizing free radicals in the blood and tissue, these compounds are thought to enhance the effectiveness of other antioxidants. This is especially true of vitamins C & E.

Experts agree that the procyanidin compounds found in grape seed extract are beneficial in treating vascular disorders such as fragile capillaries and poor circulation in the veins. By sticking to the walls of the capillaries, these components make them less likely to break down with the effects of aging.

One European study concluded that a chronic condition of circulation in the veins was quickly relieved with treatment of grape seed extract. It has also been beneficial in treating a condition characterized by an excessive accumulation of fluid in tissue called edema.

Grape seed extract is also a choice popular among many for reducing blood pressure in people with hypertension. A 1998 study by cardiovascular researchers at the University of California, Davis (UCD) found that flavonoids in the extract helped increase flow in blood vessels, contributing to better blood pressure levels.

The components in the extract are also antioxidants, or free radical scavengers, that aid in the prevention of some age-related cancers and atherosclerosis.

Grape seed extract may also be beneficial in the treatment & prevention of cancer. Researchers at Creighton University, Georgetown University Medical Center, and the University of Nebraska at Omaha, conducted a study in 1998, which indicated that human cancer cells were significantly inhibited and sometimes killed by grape seed extract while the growth of normal healthy cells was promoted. The extract was effective in killing 34-48% of breast, lung, and stomach cancer cells.

Grape seed extract has been found to be beneficial in treating several respiratory conditions, including asthma, emphysema, allergies, and sinusitis.

Grape seed extract is generally available in 50 mg and 100 mg capsules. The adult daily dosage has been estimated at up to 150-200 mg, or 50 mg per 50 lbs of body weight. To be effective, the label should indicate about 75-80% proanthocyanidins.

* Important note: The recommended doses are for those over age 18. Always check herb and vitamin use with your child’s health care practitioner prior to administering them.